Following Saturday's heroics, three of our sides were in the hat for the draw made on Sunday afternoon.
The ties will take place over the last weekend of this month, with a £120,000 cheque on offer.
Wrexham, after their win over Coventry City yesterday teatime, are at home to Championship high-fliers Sheffield United.
We could have another couple of National League sides through if Chesterfield see off West Bromwich Albion a week on Tuesday, Bristol City or Swansea await the Spireites if they come through their replay unscathed.
Last year's heroes Boreham Wood will see Cardiff City or Leeds United head to Meadow Park - that if they can sort the business themselves and see off Accrington Stanley in their replay.
The draw in full:
Preston North End v Tottenham
Southampton v Blackpool
Wrexham v Sheffield United
Ipswich Town v Burnley
Manchester United v Reading
Luton or Wigan v Grimsby Town
Derby County v West Ham United
Stoke City v Aston Villa or Stevenage
Blackburn Rovers v Forest Green or Birmingham
Walsall v Leicester City
Sheffield Wednesday v Fleetwood Town
Manchester City or Chelsea v Oxford or Arsenal
Bristol City or Swansea v Chesterfield or West Brom
Brighton v Liverpool or Wolves
Fulham v Sunderland
Boreham Wood or Accrington Stanley v Cardiff City or Leeds United