Stanley, second in League Two, visit the Vanarama National League club hoping to avoid a potential upset in a tie that holds added meaning for one of their forwards.
Jackson was born in Bradford and played for Guiseley in their youth team - now he's set to return to a place pivotal in his career.
“The FA Cup is still very special in my mind,” he told Accrington's website. “I haven’t played much in it at all. I got a few minutes for Grimsby away at Bolton but this will be my first start in the FA Cup Proper – if I get the chance to.
“I’m looking forward to it and it’s a nice draw for myself. I used to play at Guiseley when I was younger, for their U16s, and my family live close by to Nethermoor Park so it will be special to have a few people there watching me play, hopefully we win and I can score a couple of goals!
“I’m not one of those players who want to rest in a cup game, it’s a big game and I want to play in as many rounds as possible this year, it’s up to the gaffer but I certainly don’t want to miss out on Sunday.”
Accrington head into the tie off a 4-1 win over Barnet while Guiseley claimed an impressive win at Woking.
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