The current top seven will be looking over their shoulders at the chasing pack who are still in the running.
After a rollercoaster season, Chester know they simply have to win at Ashton United.
This game could spell the end of the Blues' promotion challenge with defeat, however a loss for the home side could see them relegated.
Defeat for the Robins and a win for Guiseley at Blyth Spartans will see them drop to the seventh tier.
Leamington have hit a bit of good form in recent weeks - just one defeat in six.
But Kidderminster will be hoping for a repeat of their 4-0 over the Brakes earlier in the season to continue their charge.
Bradford (Park Avenue) could all but cement their play-off place if they avoid defeat at Darlington.
And Spennymoor Town will guarantee a shot at glory if they can down Steve Watson's York side.
Brackley Town guaranteed themselves another shot at promotion midweek.
Home is where the heart is for the Saints who haven't lost at St James Park since the first day of December. Boston are in town looking to finish their season on a high.
Elsewhere, two sides wondering what could've been meet each other - Southport travel to Curzon Ashton.
Friday's National League North fixtures:
Ashton United v Chester
Blyth Spartans v Guiseley
Brackley Town v Boston United
Curzon Ashton v Southport
Darlington v Bradford (Park Avenue)
Kidderminster Harriers v Leamington
York City v Spennymoor Town